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NGM Biopharmaceuticals, Inc.

https://www.ngmbio.com/

Latest From NGM Biopharmaceuticals, Inc.

Panic Not, Say Analysts As Apellis’s Syfovre Launch Is Beset By Retinal Vasculitis Events

The US firm’s Syfovre for geographic atrophy due to age-related macular degeneration was linked with a handful of cases of occlusive retinal vasculitis, according to a letter published by a top retinal society, but most analysts believe there is a reasonable explanation.

Ophthalmic Safety

Finance Watch: Lucky Few Raise Cash While Many Public Biotechs Cut Costs

Public Company Edition: ImmunoGen received the first $75m under a $175m term loan, while Protagonist raised $100m in a follow-on offering, but companies with bankruptcy filings and job cuts outpaced those accessing new capital by a wide margin in late March and early April.

Financing Restructuring

Intercept, Madrigal Get Ready For NASH Commercialization

With a 22 June US FDA action date for obeticholic acid in non-alcoholic steatohepatitis, Intercept is thinking ahead to launch plans. Madrigal said it plans a Q2 filing for its NASH drug and hopes to find an ex-US commercial partner.

Business Strategies Clinical Trials

NGM’s Second Phase II Miss Raises Questions For Option Deal With Merck

NGM said a Merck-partnered C3 inhibiting antibody has failed a Phase II study in geographic atrophy, after the biotech’s wholly owned NASH candidate missed in a Phase IIb study in 2021.

Clinical Trials Business Strategies
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