Listerine comparability clinicals requirement urged by Warner-Lambert.
This article was originally published in The Tan Sheet
Executive Summary
LISTERINE COMPARABILITY CLINICALS REQUIREMENT URGED by Warner-Lambert for products containing the same essential oil combination. At a May 27 meeting of FDA's Dental Plaque Subcommittee in Gaithersburg, Md., Warner-Lambert Consumer Healthcare R&D Dental Affairs Director Michael Barnett, DDS, suggested all marketers using the same essential oil active ingredients as Listerine be required to conduct six-month effectiveness studies because antimicrobial ingredients can be "adversely affected by excipients in a formulation."