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Failed ALTTO Breast Cancer Trial Casts Doubt On pCR Marker

This article was originally published in The Pink Sheet Daily

Executive Summary

New surrogate marker used to speed development and approval of breast cancer drugs fails to match with better outcomes in ALTTO breast cancer study of Tykerb with Herceptin, featured in ASCO plenary session. Results have “profound implications” for drug development, says outgoing ASCO president Clifford Hudis.

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