Vytorin, Zetia Labeling Adds Precaution On Cyclosporine Coadministration
This article was originally published in The Pink Sheet Daily
Executive Summary
Revised labeling for the Merck/Schering-Plough products recommends caution when coadministering ezetimibe and cyclosporine. In healthy patients, coadministration of cyclosporine and ezetimibe was associated with a 15% increase in cyclosporine AUC, labeling states.