Merck agent reduces niacin flushing
Executive Summary
Data on Merck's MK-0524, an investigational DP1-receptor antagonist, shows a reduction in flushing in dyslipidemia patients on extended-release niacin. In data presented Nov. 16 at the American Heart Association's Scientific Sessions in Chicago, 37% of patients taking MK-0524 plus niacin reported flushing compared to 61% of patients treated with niacin alone. Merck is in clinical trials for MK-0524a, a fixed-dose combination of niacin and MK-0524 (1"The Pink Sheet" Oct. 2, 2006, In Brief)...