Vitamin E study
This article was originally published in The Tan Sheet
Executive Summary
A National Institutes of Health-funded study establishes a framework for future studies assessing the ability of therapeutic agents to suppress oxidative stress in humans by providing information on the dosage of vitamin E that decreases systemic oxidant stress in vivo in humans, according to the authors of the study recently published in Free Radical Biology & Medicine. The trial included a time-course study on participants supplemented with 3,200 IU/day of vitamin E for 20 weeks and found maximum suppression of plasma F2-isoprostane concentrations did not occur until 16 weeks of supplementation, L. Jackson Roberts II, Vanderbilt University Pharmacology and Medicine departments, et al., say. Researchers also conducted a dose-ranging study in which participants were supplemented with various doses of vitamin E every day for 16 weeks, and found a linear trend between the dosage of vitamin E and percentage reduction in plasma F2-isoprostane concentrations...