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Folic acid & NTD’s

This article was originally published in The Tan Sheet

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Public health policy should be guided by "specification of the dose-response relation between extra folic acid and the reduction in the risk of neural tube defects," Nicholas Wald writes in Jan. 8 New England Journal of Medicine. A study by Sheldon Rotherberg, MD, et al. published in the same issue finds autoantibodies acting to reduce cellular uptake of folate in women whose pregnancies are complicated by NTDs. The experimenters recommend further study to determine a possible causal relationship between maternal autoantibodies and neural tube defects...

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