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Wyeth Indux

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Executive Summary

Approval of long bone fracture healing indication for recombinant bone morphogenic protein expected by early 2002, American Home Products CEO Robert Essner tells analysts May 16. Indux (BMP-2) is in Phase III for three indications: long bone fracture, spinal fusion (with Medtronic/Sofamor Danek) and dental craniofacial use. In Phase III trials, standard care of a tibia fracture healed in 20 weeks, while standard care with Indux healed in 14 weeks with more complete bone fusion. Indux sales are expected to reach $500 mil. by 2004, Essner says

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