In Brief: Atrix Labs Atridox

Executive Summary

Atrix Labs Atridox: Doxycycline polymer delivery system for periodontal disease to be filed in early 1997, Fort Collins, Colo.-based Atrix says. Atridox shows clinical and statistical superiority to placebo and equivalence to mechanical scaling and route planing in Phase III trials, the firm reports Aug. 26. Atridox is "applied to the infected periodontal pocket as a fluid, where it molds to the shape of the problem area and quickly solidifies, releasing the drug" for a week, Atrix reports. The drug was studied in 758 subjects over nine months...