Fluconazole should not be standard fungus prophylaxis for people with HIV -- new PHS/IDSA guidelines.

Executive Summary

FLUCONAZOLE SHOULD NOT BE USED FOR ROUTINE HIV PROPHYLAXIS of the fungal infections candidiasis and cryptococcosis, the Public Health Service and the Infectious Diseases Society of America recommend in new guidelines for prevention of opportunistic infections. Pfizer's Diflucan (fluconazole) is approved for treatment of oropharyngeal and esophageal candidiasis and cryptococcal meningitis often related to HIV/AIDS; as prophylaxis for candidiasis in patients who undergo bone marrow transplantation who receive chemotherapy; and, most recently, for treatment of vaginal candidiasis ("The Pink Sheet" July 11, p. 8).