In Brief: Immunex' Thioplex (thiopeta)
Executive Summary
Immunex' Thioplex (thiopeta): Freeze-dried, lyophilized powder formulation of the alkylating anti-cancer agent approved by FDA on Dec. 22. Developed by Lederle Labs, thiopeta is widely used in treating bladder, breast and ovarian cancers, Immunex says. A patent application for the manufacturing process for the freeze-dried formulation, which gives the drug longer shelf-life, is pending. Thioplex will be available beginning in March. Lederle Parenterals will manufacture Thioplex in Puerto Rico...