SmithKline Beecham's Kytril

Executive Summary

Comparative trial of Kytril (granisetron) to Glaxo's Zofran (ondansetron) in 533 patients with lung cancer found no significant differences in "anti-emetic efficacy between Kytril 10 mcg/kg versus Zofran .15 mg/kg, SB says. The study, presented at the 7th World Conference on Lung Cancer, is "the first head-to- head trial of Kytril injection. and Zofran injection at dosing regimens marketed in the U.S.," SB declares. In the full study of 992 patients with all types of cancer, no differences in side effects were seen