GenDerm's Zonalon (doxepin cream, 5%)

Executive Summary

Topical antihistamine expected to be in pharmacies by the end of April following April I approval. Direct price to wholesalers for a 30 g tube is $16.50, GenDerm says. Cream is indicated for "short-term (up to eight days) management of moderate pruritus in adult patients with the following forms of eczematous dermatitis: atopic dermatitis and lichen simplex chronicus," labeling states. Labeling warns that "drowsiness occurs in over 20% of patients treated with Zonalon cream, especially in patients receiving treatment to greater than 10% of their body surface area"