Warner-Lambert
Executive Summary
Has filed four NDAs since November 1990. Last December, the firm submitted an NDA for Estrostep, a once-daily triphasic oral contraceptive that combines estrogens in a formula designed to reduce side effects and for Accuretic, an antihypertensive that crosses W-L's ace inhibitor Accupril with the diuretic hydrochlorothiazide. On Feb. 14, the company submitted an NDA for pentostatin, an orphan drug for the treatment of hairy cell leukemia. The company's grand slam filing was completed on Feb. 25, with the submission of Lopid SR, a once-daily version of the cholesterol regulator Lopid.